Tuesday, January 8, 2008

Tel Aviv University licenses cinnamon extract as HIV, flu cure

News release from Frutarom

Frutarom Industries Ltd. and Ramot at Tel Aviv University Ltd. signed an exclusive agreement to commercialize unique knowhow (patent pending) developed by Professor Michael Ovadia of Tel Aviv University, to produce an innovative extract from cinnamon with anti viral properties.

The comprehensive research performed in Professor Ovadia’s laboratory demonstrated the extract’s ability to rapidly neutralize a broad range of viruses that cause infectious diseases in both humans and animal, such as human and avian influenza, herpes (HSV-1) and human immunodeficiency virus (HIV-1). Another unique activity of this innovative extract is its ability to boost the immune system against viruses, demonstrated by the ability to serve as a vaccination agent in chicken embryos infected with Newcastle disease virus (NDV). Trials performed together with a veterinary company showed that chicken embryos can be vaccinated against the NDV virus while they are still in the egg and in so doing, significantly improve the efficiency of the vaccine’s administration, increase success rates and reduce mortality.

The agreement with Ramot gives Frutarom an exclusive global license to commercialize the knowhow in order to manufacture and market the unique natural extract, based on knowhow currently being patented. Frutarom intends to market this unique product to the nutraceutical, functional food, health food and animal feed industries and to further develop the knowhow as a drug for humans and animals as part of the Company’s unique natural product offering. Frutarom will invest in further research and development of this unique product and additional applications within Frutarom’s fields of activity. Professor Michael Ovadia will lead the research.

Frutarom will use its considerable knowhow in natural product manufacturing for the research, development and scaling up of the product’s manufacturing process in accordance with international quality standards so as to achieve industrial scale production and commercialization. Frutarom estimates that the product will be launched in about a year.

The cooperation with Ramot is part of Frutarom’s broad strategic plan to expand Frutarom’s offering of unique natural products and to strengthen Frutarom’s position and standing as a leading global supplier of natural products and functional food ingredients for tasty and healthy solutions. As part of this strategy, Frutarom invests in and cooperates with start-up companies, research institutes and universities that develop innovative and unique technologies. This supports Frutarom’s own ongoing research and development activities, carried out in-house by its R&D teams throughout the world. In the last year, Frutarom initiated several such alliances: exclusive cooperation with D-Herb, of the NGT technological incubator in Nazareth, Israel, to produce and market a unique herbal extract that is used to reduce and stabilize glucose levels in diabetecs; exclusive cooperation with Magnetika Interactive Ltd., to produce, market and sell products enriched with Omega-3 fatty acid; and exclusive cooperation with CapsiVit Biotechnology Ltd. to commercialize unique knowhow developed by the Vulcani Institute in Israel to produce a natural extract from the Capsicum annuum L. plant as a highly bio-available source of carotenoids and particularly capsanthin; and others.

Ori Yehudai, President and Chief Executive Officer of Frutarom: “The addition of this unique, innovative product to Frutarom’s varied offering of natural products will contribute to the continued realization of Frutarom’s rapid growth strategy, with emphasis on natural products intended for segments with higher than average growth rates, such as functional food, health food and nutraceuticals. Frutarom’s alliances with start-ups, research institutes and universities strengthen and expand our solid pipeline of projects and natural, innovative products that we intend to market in the coming years. Frutarom continues to work on creating additional strategic collaborations.”

Dr. Yehuda Niv, CEO of Ramot at Tel Aviv University Ltd.: “The discovery and development of this unique extract are an example of research conducted at Tel Aviv University that is both creative and leading in its field. Granting the license to Frutarom is the logical step to further develop this scientific discovery into health, biotechnology and consumer products.'' Dr. Niv added, ''Ramot fosters close relationships between Tel Aviv University researchers and industry to enable the translation of such scientific findings into novel products that will benefit the lives of people worldwide.''

As part of the cooperation, Frutarom will utilize its global reach, which includes over 5,000 international and local customers – among them leading companies in their fields – in more than 120 countries, as well as Frutarom’s sales and marketing organization and rich experience in industrial production, including extensive knowledge in scaling up production processes and commercialization

Frutarom

Frutarom is a multinational company operating in the global flavor extracts and fine ingredients markets. Frutarom has significant manufacturing and development centers on three continents and markets its products to more than 5,000 customers in over 120 countries. Frutarom’s products are intended for the food and beverage, flavor and fragrance, pharmaceutical, nutraceutical, health food, functional food, food supplement and cosmetic industries.

Frutarom operates two main divisions:

* The Flavors Division develops, manufactures and markets flavor compounds and food systems.

* The Fine Ingredients Division develops, manufactures and markets natural flavor extracts, natural functional food ingredients, natural pharma/nutraceutical extracts, essential oils and unique citrus products and aromatic chemicals.

Frutarom’s products are produced at its facilities in the USA, the UK, Switzerland, Germany, Israel, Denmark, China, and Turkey. The company’s global marketing network includes marketing departments in Israel, the USA, the UK, Switzerland, Germany, Belgium, Holland, Denmark, France, Hungary, Romania, Russia, Ukraine, Kazakhstan, Belarus, Turkey, Brazil, Mexico, China, Japan, Hong Kong, India, and Indonesia. The Company also has agents and local distributors throughout the world. Frutarom employs some 1,150 employees worldwide.

Tel Aviv University

Founded in 1963, Tel Aviv University is one of Israel’s foremost research and teaching universities. Located in Israel’s cultural, financial and industrial heartland, Tel Aviv University is at the forefront of basic and applied research in a wide variety of scientific research disciplines, including engineering, exact sciences, life sciences, medicine, social sciences, management, law, humanities and the arts.

Ramot at Tel Aviv University

Ramot is the technology transfer company of Tel Aviv University. Ramot fosters, initiates, leads, and manages the transfer of new technologies from the university laboratories to the marketplace, by performing all activities relating to the protection and commercialization of inventions and discoveries made by faculty, students and other researchers of Tel Aviv University. Ramot provides a dynamic interface connecting industry to leading edge science and innovation, offering new business opportunities in a wide variety of emerging markets.

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